Nature


Luciano A. Marraffini, Erik J. Sontheimer. Self versus non-self discrimination during CRISPR RNA-directed immunity // Nature, 463, 568-571 (28 January 2010)

[HTML] from nih.gov…, EJ Sontheimer - Nature2010 - nature.com
... Self versus non-self discrimination during CRISPR RNA-directed immunityLuciano A. Marraffini
1 & Erik JSontheimer 1. Department of Biochemistry, Molecular Biology and Cell Biology,
Northwestern University, 2205 Tech Drive, Evanston, Illinois 60208, USA. ... 
Cited by 10 - Related articles - All 9 versions


LA Marraffini… - Nature Reviews Genetics, 2010 - nature.com
Sequence-directed genetic interference pathways control gene expression and preserve genome 
integrity in all kingdoms of life. The importance of such pathways is highlighted by the extensive 
study of RNA interference (RNAi) and related processes in eukaryotes. In many bacteria ... 
Cited by 10 - Related articles - All 8 versions
SJ Labrie, JE Samson… - Nature Reviews Microbiology, 2010 - nature.com
Phages are now acknowledged as the most abundant microorganisms on the planet and are 
also possibly the most diversified. This diversity is mostly driven by their dynamic adaptation 
when facing selective pressure such as phage resistance mechanisms, which are ... 
Cited by 6 - Related articles - All 4 versions
K Pougach, E Semenova, E Bogdanova… - Molecular … - interscience.wiley.com
CRISPR/Cas, bacterial and archaeal systems of inter- ference with foreign genetic elements 
such as viruses or plasmids, consist of DNA loci called CRISPR cas- settes (a set of variable 
spacers regularly separated by palindromic repeats) and associated cas genes. When a ... 
Cited by 2 - Related articles - All 5 versions
[HTML] from nih.govPF Vale… - Proceedings of the Royal …, 2010 - rspb.royalsocietypublishing.org
Bacteria can acquire heritable immunity to viral (phage) enemies by incorporating phage DNA 
into their own genome. This mechanism of anti-viral defence, known by the acronym 
CRISPR, simultaneously stores detailed information about current and past enemies and ... 
Cited by 1 - Related articles - All 5 versions
SM Hedrick, IL Ch'en… - Immunological reviews, 2010 - interscience.wiley.com
Ó 2010 John Wiley & Sons A/S • Immunological Reviews 236/2010 ... Stephen M. Hedrick Irene 
L. Ch'en Bryce N. Alves ... Authors' address Stephen M. Hedrick1, Irene L. Ch'en1, Bryce N. Alves1 
1Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA. 
Cited by 1 - Related articles - All 5 versions
J Carte, NT Pfister, MM Compton, RM Terns… - RNA, 2010 - rnajournal.cshlp.org
Page 1. 10.1261/rna.2230110 Access the most recent version at doi: published online
September 30, 2010 RNA Jason Carte, Neil T. Pfister, Mark M. Compton, et al. Binding
and cleavage of CRISPR RNA by Cas6 P<P Published ... 
Related articles - All 3 versions
LA Marraffini - Future Microbiol., 2010 - Future Medicine
Bacteria have the ability to evolve fast, mainly by acquiring genetic material from related or unrelated 
species, a process known as horizontal or lateral gene transfer (HGT). There are three basic 
routes for the transfer of DNA between bacteria: transformation, transduction and ... 
Related articles - All 2 versions
[PDF] from weizmann.ac.ilA Stern, L Keren, O Wurtzel, G Amitai… - Trends in Genetics, 2010 - Elsevier
The recently discovered prokaryotic immune system known as CRISPR (clustered regularly interspaced 
short palindromic repeats) is based on small RNAs ('spacers') that restrict phage and plasmid 
infection. It has been hypothesized that CRISPRs can also regulate self gene expression ... 
Related articles - All 6 versions
[HTML] from plos.orgM Touchon, EPC Rocha… - PloS one, 2010 - dx.plos.org
Prokaryotes thrive in spite of the vast number and diversity of their viruses. This partly results 
from the evolution of mechanisms to inactivate or silence the action of exogenous DNA. Among 
these, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) are unique ... 
Related articles - Cached - All 7 versions
H Liesegang, AK Kaster, A Wiezer… - Journal of …, 2010 - Am Soc Microbiol
Methanothermobacter marburgensis (DSM 2133) (formerly Methanobacterium thermoautotrophicum 
strain Marburg), a member of the Methanobacteriales (2), was isolated in 1978 from anaerobic 
sewage sludge in Marburg, Germany (5). The hydrogenotrophic methanogen grows even ...
Subpages (1): Review
Comments